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Skip to main content area home about evidence-based content access options subscribe dynamed overview dynamed mission editorial team editorial board citing dynamed cme weekly update archived updates reviews news & events further reading careers radical prostatectomy may not reduce mortality in most men with localized prostate cancer compared to watchful waiting aafp scientific assembly stop by the ebsco booth at american academy of family physicians (aafp) scientific assembly in philadelphia, pa, october 17-20, 2012. Learn more join the dynamed team looking for a change? The dynamed editorial team is expanding and looking for medical writers! buy viagra online from canada Learn more dynamed ranks highest among clincial reference resources dynamedâ® has ranked highest among ten online clinical resources in a new study in the journal of clinical epidemiology. Learn more klas report dynamed rated higher than other disease reference tools in new klas report on clinical decision support. Learn more dynamed weekly update sign up for dynamed weekly update, a compilation of one to five articles selected from dynamed's systematic literature surveillance as articles most likely to change clinical practice.   free cme credit is available for each issue. Email: * week ending july 27, 2012 prostate cancer is the most common cancer in men (not counting skin cancer) and the second most common cause of cancer deaths in men, but many aspects of the management of this disease are controversial. Psa screening has become common over the last 2 decades, and has contributed to increased detection rates of early stage low-risk disease (of note, the united states preventive services task force [uspstf] recently issued a statement recommending against routine prostate-specific antigen [psa] screening for all men, regardless of age [ann intern med 2012 may 21 early online] [dynamed weekly update vol 7, issue 22])  the best treatment for men with low-risk prostate cancer remains unclear.  at the extremes are radical prostatectomy and watchful waiting, but comparative efficacy studies have been inconclusive to date (cochrane database syst rev 2010 nov 10;(11):cd006590). cheapest viagra in uk   the pivot trial compared radical prostatectomy to watchful waiting in 731 men with localized prostate cancer detected by psa testing.  men ≤ 75 years old (mean age 67 years) were randomized to radical prostatectomy vs. Watchful waiting from 1994 to 2002 and were followed for up to 15 years (median follow-up 10 years).  at baseline, all men had psa < 50 ng/ml and life expectancy of ≥ 10 years. viagra pharmacy uk During the trial, 77. 2% of the radical prostatectomy group and 79. 6% of the watchful waiting group received their allocated treatment. viagra online forum  there was no significant 2000 difference in all-cause mortality between the 2 groups (47% vs. viagra for sale 49. 9%) (level 2 [mid-level] evidence) in the overall intention-to-treat analysis, but prostatectomy was associated with a trend toward reduced prostate cancer-related mortality (5. 8% vs. Viagra online without prescription 8. 4%, p = 0. 09).  in a subgroup analysis of 251 men with psa > 10 ng/ml at baseline, however, prostatectomy was associated with significant reductions in both all-cause mortality (48. 4% vs. 61. buy viagra birmingham 6%, p < 0. 05, nnt 8) and prostate cancer-related mortality (5. viagra for sale 6% vs. viagra pill identification 12. 8%, p < 0. 05, nnt 14) (n engl j med 2012 jul 19;367(3):203).   for more information, see the prostate cancer topic in dynamed. 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